diff --git a/NEWS b/NEWS
index ab49999..ee60eea 100644
--- a/NEWS
+++ b/NEWS
@@ -14,6 +14,8 @@ Changes from 0.13.0
      ``(eval `(+ 1 ~(HyInteger n)))``
    * Literal `Inf`s and `NaN`s must now be capitalized like that
    * `get` is available as a function
+   * new `comment` macro
+   * support EDN `#_` syntax to discard the next term
 
    [ Bug Fixes ]
    * Numeric literals are no longer parsed as symbols when followed by a dot
diff --git a/docs/language/api.rst b/docs/language/api.rst
index bfac38e..a097d8b 100644
--- a/docs/language/api.rst
+++ b/docs/language/api.rst
@@ -89,6 +89,31 @@ the error ``Keyword argument :foo needs a value``. To avoid this, you can quote
 the keyword, as in ``(f ':foo)``, or use it as the value of another keyword
 argument, as in ``(f :arg :foo)``.
 
+discard prefix
+--------------
+
+Hy supports the Extensible Data Notation discard prefix, like Clojure.
+Any form prefixed with ``#_`` is discarded instead of compiled.
+This completely removes the form so it doesn't evaluate to anything,
+not even None.
+It's often more useful than linewise comments for commenting out a
+form, because it respects code structure even when part of another
+form is on the same line. For example:
+
+.. code-block:: clj
+
+   => (print "Hy" "cruel" "World!")
+   Hy cruel World!
+   => (print "Hy" #_"cruel" "World!")
+   Hy World!
+   => (+ 1 1 (print "Math is hard!"))
+   Math is hard!
+   Traceback (most recent call last):
+      ...
+   TypeError: unsupported operand type(s) for +: 'int' and 'NoneType'
+   => (+ 1 1 #_(print "Math is hard!"))
+   2
+
 Built-Ins
 =========
 
@@ -328,6 +353,30 @@ as the user enters *k*.
                   (print "Try again")))
 
 
+comment
+----
+
+The ``comment`` macro ignores its body and always expands to ``None``.
+Unlike linewise comments, the body of the ``comment`` macro must
+be grammatically valid Hy, so the compiler can tell where the comment ends.
+Besides the semicolon linewise comments,
+Hy also has the ``#_`` discard prefix syntax to discard the next form.
+This is completely discarded and doesn't expand to anything, not even ``None``.
+
+.. code-block:: clj
+
+   => (print (comment <h1>Suprise!</h1>
+   ...                <p>You'd be surprised what's grammatically valid in Hy.</p>
+   ...                <p>(Keep delimiters in balance, and you're mostly good to go.)</p>)
+   ...        "Hy")
+   None Hy
+   => (print #_(comment <h1>Suprise!</h1>
+   ...                  <p>You'd be surprised what's grammatically valid in Hy.</p>
+   ...                  <p>(Keep delimiters in balance, and you're mostly good to go.)</p>))
+   ...        "Hy")
+   Hy
+
+
 cond
 ----
 
diff --git a/hy/core/macros.hy b/hy/core/macros.hy
index 56efc3e..1d0734c 100644
--- a/hy/core/macros.hy
+++ b/hy/core/macros.hy
@@ -214,3 +214,7 @@
   (setv decorators (cut expr None -1)
         fndef (get expr -1))
   `(with-decorator ~@decorators ~fndef))
+
+(defmacro comment [&rest body]
+  "Ignores body and always expands to None"
+  None)
diff --git a/hy/lex/lexer.py b/hy/lex/lexer.py
index b73c284..cb021a0 100755
--- a/hy/lex/lexer.py
+++ b/hy/lex/lexer.py
@@ -25,6 +25,7 @@ lg.add('QUOTE', r'\'%s' % end_quote)
 lg.add('QUASIQUOTE', r'`%s' % end_quote)
 lg.add('UNQUOTESPLICE', r'~@%s' % end_quote)
 lg.add('UNQUOTE', r'~%s' % end_quote)
+lg.add('DISCARD', r'#_')
 lg.add('HASHSTARS', r'#\*+')
 lg.add('HASHOTHER', r'#%s' % identifier)
 
diff --git a/hy/lex/parser.py b/hy/lex/parser.py
index 0c73652..efac562 100755
--- a/hy/lex/parser.py
+++ b/hy/lex/parser.py
@@ -153,6 +153,17 @@ def list_contents_single(p):
     return [p[0]]
 
 
+@pg.production("list_contents : DISCARD term discarded_list_contents")
+def list_contents_empty(p):
+    return []
+
+
+@pg.production("discarded_list_contents : DISCARD term discarded_list_contents")
+@pg.production("discarded_list_contents :")
+def discarded_list_contents(p):
+    pass
+
+
 @pg.production("term : identifier")
 @pg.production("term : paren")
 @pg.production("term : dict")
@@ -163,6 +174,11 @@ def term(p):
     return p[0]
 
 
+@pg.production("term : DISCARD term term")
+def term_discard(p):
+    return p[2]
+
+
 @pg.production("term : QUOTE term")
 @set_quote_boundaries
 def term_quote(p):
diff --git a/tests/native_tests/core.hy b/tests/native_tests/core.hy
index 4cff830..d9455ef 100644
--- a/tests/native_tests/core.hy
+++ b/tests/native_tests/core.hy
@@ -678,3 +678,7 @@ result['y in globals'] = 'y' in globals()")
                 [1 6 21])
   (assert-equal ((juxt identity) 42)
                 [42]))
+
+(defn test-comment []
+  (assert-none (comment <h1>This is merely a comment.</h1>
+                        <p> Move along. (Nothing to see here.)</p>)))
diff --git a/tests/test_lex.py b/tests/test_lex.py
index 2f7a207..247ae4d 100644
--- a/tests/test_lex.py
+++ b/tests/test_lex.py
@@ -4,7 +4,7 @@
 
 from math import isnan
 from hy.models import (HyExpression, HyInteger, HyFloat, HyComplex, HySymbol,
-                       HyString, HyDict, HyList, HySet, HyCons)
+                       HyString, HyDict, HyList, HySet, HyCons, HyKeyword)
 from hy.lex import LexException, PrematureEndOfInput, tokenize
 import pytest
 
@@ -423,3 +423,72 @@ def test_cons_list():
     entry = tokenize("(a b . {})")[0]
     assert entry == HyDict([HySymbol("a"), HySymbol("b")])
     assert type(entry) == HyDict
+
+def test_discard():
+    """Check that discarded terms are removed properly."""
+    # empty
+    assert tokenize("") == []
+    # single
+    assert tokenize("#_1") == []
+    # multiple
+    assert tokenize("#_1 #_2") == []
+    assert tokenize("#_1 #_2 #_3") == []
+    # nested discard
+    assert tokenize("#_ #_1 2") == []
+    assert tokenize("#_ #_ #_1 2 3") == []
+    # trailing
+    assert tokenize("0") == [0]
+    assert tokenize("0 #_1") == [0]
+    assert tokenize("0 #_1 #_2") == [0]
+    # leading
+    assert tokenize("2") == [2]
+    assert tokenize("#_1 2") == [2]
+    assert tokenize("#_0 #_1 2") == [2]
+    assert tokenize("#_ #_0 1 2") == [2]
+    # both
+    assert tokenize("#_1 2 #_3") == [2]
+    assert tokenize("#_0 #_1 2 #_ #_3 4") == [2]
+    # inside
+    assert tokenize("0 #_1 2") == [0, 2]
+    assert tokenize("0 #_1 #_2 3") == [0, 3]
+    assert tokenize("0 #_ #_1 2 3") == [0, 3]
+    # in HyList
+    assert tokenize("[]") == [HyList([])]
+    assert tokenize("[#_1]") == [HyList([])]
+    assert tokenize("[#_1 #_2]") == [HyList([])]
+    assert tokenize("[#_ #_1 2]") == [HyList([])]
+    assert tokenize("[0]") == [HyList([HyInteger(0)])]
+    assert tokenize("[0 #_1]") == [HyList([HyInteger(0)])]
+    assert tokenize("[0 #_1 #_2]") == [HyList([HyInteger(0)])]
+    assert tokenize("[2]") == [HyList([HyInteger(2)])]
+    assert tokenize("[#_1 2]") == [HyList([HyInteger(2)])]
+    assert tokenize("[#_0 #_1 2]") == [HyList([HyInteger(2)])]
+    assert tokenize("[#_ #_0 1 2]") == [HyList([HyInteger(2)])]
+    # in HySet
+    assert tokenize("#{}") == [HySet()]
+    assert tokenize("#{#_1}") == [HySet()]
+    assert tokenize("#{0 #_1}") == [HySet([HyInteger(0)])]
+    assert tokenize("#{#_1 0}") == [HySet([HyInteger(0)])]
+    # in HyDict
+    assert tokenize("{}") == [HyDict()]
+    assert tokenize("{#_1}") == [HyDict()]
+    assert tokenize("{#_0 1 2}") == [HyDict([HyInteger(1), HyInteger(2)])]
+    assert tokenize("{1 #_0 2}") == [HyDict([HyInteger(1), HyInteger(2)])]
+    assert tokenize("{1 2 #_0}") == [HyDict([HyInteger(1), HyInteger(2)])]
+    # in HyExpression
+    assert tokenize("()") == [HyExpression()]
+    assert tokenize("(#_foo)") == [HyExpression()]
+    assert tokenize("(#_foo bar)") == [HyExpression([HySymbol("bar")])]
+    assert tokenize("(foo #_bar)") == [HyExpression([HySymbol("foo")])]
+    assert tokenize("(foo :bar 1)") == [HyExpression([HySymbol("foo"), HyKeyword(":bar"), HyInteger(1)])]
+    assert tokenize("(foo #_:bar 1)") == [HyExpression([HySymbol("foo"), HyInteger(1)])]
+    assert tokenize("(foo :bar #_1)") == [HyExpression([HySymbol("foo"), HyKeyword(":bar")])]
+    # discard term with nesting
+    assert tokenize("[1 2 #_[a b c [d e [f g] h]] 3 4]") == [
+        HyList([HyInteger(1), HyInteger(2), HyInteger(3), HyInteger(4)])
+    ]
+    # discard with other prefix syntax
+    assert tokenize("a #_'b c") == [HySymbol("a"), HySymbol("c")]
+    assert tokenize("a '#_b c") == [HySymbol("a"), HyExpression([HySymbol("quote"), HySymbol("c")])]
+    assert tokenize("a '#_b #_c d") == [HySymbol("a"), HyExpression([HySymbol("quote"), HySymbol("d")])]
+    assert tokenize("a '#_ #_b c d") == [HySymbol("a"), HyExpression([HySymbol("quote"), HySymbol("d")])]